Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency.

The inherited deficiency of adenosine deaminase (adenosine aminohydrolase; EC 3.5.4.4) activity in humans is associated with an immunodeficiency. Some of the immunodeficient and enzyme-deficient patients respond immunologically to periodic infusions of irradiated erythrocytes containing adenosine de...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Cohen, A, Hirschhorn, R, Horowitz, S D, Rubinstein, A, Polmar, S H, Hong, R, Martin, D W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.472
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