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Pyrrolo- and Pyridomorphinans: Non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists

Opioid ligands have found use in a number of therapeutic areas, including for the treatment of pain and opiate addiction (using agonists) and alcohol addiction (using antagonists such as naltrexone and nalmefene). The reaction of imines, derived from the opioid ligands oxymorphone and naltrexone, wi...

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Hlavní autoři: Kumar, V., Clark, M.J., Traynor, J.R., Lewis, J.W., Husbands, S.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112151/
https://ncbi.nlm.nih.gov/pubmed/24973818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.05.065
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