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Pyrrolo- and Pyridomorphinans: Non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists

Opioid ligands have found use in a number of therapeutic areas, including for the treatment of pain and opiate addiction (using agonists) and alcohol addiction (using antagonists such as naltrexone and nalmefene). The reaction of imines, derived from the opioid ligands oxymorphone and naltrexone, wi...

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Main Authors: Kumar, V., Clark, M.J., Traynor, J.R., Lewis, J.W., Husbands, S.M.
格式: Artigo
語言:Inglês
出版: 2014
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112151/
https://ncbi.nlm.nih.gov/pubmed/24973818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.05.065
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