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Pyrrolo- and Pyridomorphinans: Non-selective opioid antagonists and delta opioid agonists/mu opioid partial agonists

Opioid ligands have found use in a number of therapeutic areas, including for the treatment of pain and opiate addiction (using agonists) and alcohol addiction (using antagonists such as naltrexone and nalmefene). The reaction of imines, derived from the opioid ligands oxymorphone and naltrexone, wi...

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Bibliografiska uppgifter
Huvudupphovsmän: Kumar, V., Clark, M.J., Traynor, J.R., Lewis, J.W., Husbands, S.M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112151/
https://ncbi.nlm.nih.gov/pubmed/24973818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.05.065
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