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An assay for human telomeric G-quadruplex DNA binding drugs
Compounds that stabilize the G-quadruplexes formed by human telomeres can inhibit the telomerase activity and are potential cancer therapies. We have developed an assay for the screening of compounds with high affinity for human telomeric G-quadruplexes (HTG). The assay uses a thiazole orange fluore...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112084/ https://ncbi.nlm.nih.gov/pubmed/24246738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.10.030 |
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