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Aminoglycoside binding to Oxytricha Nova Telomeric DNA

Telomeric DNA sequences have been at the center stage of drug design for cancer treatment in recent years. The ability of these DNA structures to form four stranded nucleic acid structures, called G-quadruplexes, has been perceived as target for inhibiting telomerase activity vital for the longevity...

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Dettagli Bibliografici
Autori principali: Ranjan, Nihar, Andreasen, Katrine F., Kumar, Sunil, Hyde-volpe, David, Arya, Dev P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641841/
https://ncbi.nlm.nih.gov/pubmed/20886815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101517e
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