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Aminoglycoside binding to Oxytricha Nova Telomeric DNA
Telomeric DNA sequences have been at the center stage of drug design for cancer treatment in recent years. The ability of these DNA structures to form four stranded nucleic acid structures, called G-quadruplexes, has been perceived as target for inhibiting telomerase activity vital for the longevity...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641841/ https://ncbi.nlm.nih.gov/pubmed/20886815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101517e |
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