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Aminoglycoside binding to Oxytricha Nova Telomeric DNA

Telomeric DNA sequences have been at the center stage of drug design for cancer treatment in recent years. The ability of these DNA structures to form four stranded nucleic acid structures, called G-quadruplexes, has been perceived as target for inhibiting telomerase activity vital for the longevity...

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Bibliografische gegevens
Hoofdauteurs: Ranjan, Nihar, Andreasen, Katrine F., Kumar, Sunil, Hyde-volpe, David, Arya, Dev P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641841/
https://ncbi.nlm.nih.gov/pubmed/20886815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101517e
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