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Multivalency in Recognition and Antagonism of HIV TAR RNA – TAT Assembly using an Aminoglycoside Benzimidazole Scaffold

Recognition of RNA by high-affinity binding small molecules is crucial for expanding existing approaches in RNA recognition, and for the development of novel RNA binding drugs. A novel neomycin dimer benzimidazole conjugate 5 (DPA 83) was synthesized by conjugating a neomycin-dimer with benzimidazol...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Kumar, Sunil, Ranjan, Nihar, Kellish, Patrick, Gong, Changjun, Watkins, Derrick, Arya, Dev P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837457/
https://ncbi.nlm.nih.gov/pubmed/26765486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5ob02016f
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