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Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4

Developing anti-viral therapies targeting HIV-1 transcription has been hampered by the limited structural knowledge of the proteins involved. HIV-1 hijacks the cellular machinery that controls RNA polymerase II elongation through an interaction of HIV-1 Tat with the positive transcription elongation...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gu, Jianyou, Babayeva, Nigar D, Suwa, Yoshiaki, Baranovskiy, Andrey G, Price, David H, Tahirov, Tahir H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111725/
https://ncbi.nlm.nih.gov/pubmed/24727379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28756
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