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Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4
Developing anti-viral therapies targeting HIV-1 transcription has been hampered by the limited structural knowledge of the proteins involved. HIV-1 hijacks the cellular machinery that controls RNA polymerase II elongation through an interaction of HIV-1 Tat with the positive transcription elongation...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4111725/ https://ncbi.nlm.nih.gov/pubmed/24727379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28756 |
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