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Crystallization and preliminary X-ray diffraction analysis of human DNA primase

Human primase synthesizes RNA primers and transfers them to the active site of Pol α with subsequent extension with dNTPs. Human primase is a heterodimer of two subunits: a small catalytic subunit (p49) and a large subunit (p58). The structural details of the initiation and elongation steps of prime...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Baranovskiy, Andrey G., Gu, Jianyou, Babayeva, Nigar D., Agarkar, Vinod B., Suwa, Yoshiaki, Tahirov, Tahir H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936435/
https://ncbi.nlm.nih.gov/pubmed/24637758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13034432
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