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Crystallization and preliminary X-ray diffraction analysis of human DNA primase
Human primase synthesizes RNA primers and transfers them to the active site of Pol α with subsequent extension with dNTPs. Human primase is a heterodimer of two subunits: a small catalytic subunit (p49) and a large subunit (p58). The structural details of the initiation and elongation steps of prime...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3936435/ https://ncbi.nlm.nih.gov/pubmed/24637758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13034432 |
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