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Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit

In eukaryotic DNA replication, short RNA-DNA hybrid primers synthesized by primase-DNA polymerase α (Prim-Pol α) are needed to start DNA replication by the replicative DNA polymerases, Pol δ and Pol ϵ. The C terminus of the Pol α catalytic subunit (p180(C)) in complex with the B subunit (p70) regula...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Suwa, Yoshiaki, Gu, Jianyou, Baranovskiy, Andrey G., Babayeva, Nigar D., Pavlov, Youri I., Tahirov, Tahir H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505502/
https://ncbi.nlm.nih.gov/pubmed/25847248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649954
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