Crystal structure of HIV-1 Tat complexed with human P-TEFb

Regulation of the expression of the human immunodeficiency virus (HIV) genome is accomplished in large part by controlling transcription elongation. The viral protein Tat hijacks the host cell's RNA polymerase II elongation control machinery through interaction with the positive transcription e...

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Bibliographic Details
Main Authors: Tahirov, Tahir H., Babayeva, Nigar D., Varzavand, Katayoun, Cooper, Jeffrey J., Sedore, Stanley C., Price, David H.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885016/
https://ncbi.nlm.nih.gov/pubmed/20535204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09131
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