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Crystal structure of HIV-1 Tat complexed with human P-TEFb

Regulation of the expression of the human immunodeficiency virus (HIV) genome is accomplished in large part by controlling transcription elongation. The viral protein Tat hijacks the host cell's RNA polymerase II elongation control machinery through interaction with the positive transcription e...

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Détails bibliographiques
Auteurs principaux: Tahirov, Tahir H., Babayeva, Nigar D., Varzavand, Katayoun, Cooper, Jeffrey J., Sedore, Stanley C., Price, David H.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885016/
https://ncbi.nlm.nih.gov/pubmed/20535204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09131
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