Therapeutic targeting of Polo-like kinase-1 and Aurora kinases in T-cell acute lymphoblastic leukemia

Polo-like kinases (PLKs) and Aurora kinases (AKs) act as key cell cycle regulators in healthy human cells. In cancer, these protein kinases are often overexpressed and dysregulated, thus contributing to uncontrolled cell proliferation and growth. T-cell acute lymphoblastic leukemia (T-ALL) is a hete...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Spartà, Antonino Maria, Bressanin, Daniela, Chiarini, Francesca, Lonetti, Annalisa, Cappellini, Alessandra, Evangelisti, Cecilia, Evangelisti, Camilla, Melchionda, Fraia, Pession, Andrea, Bertaina, Alice, Locatelli, Franco, McCubrey, James A, Martelli, Alberto M
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2014
Sujets:
Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4111679/
https://ncbi.nlm.nih.gov/pubmed/24874015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.29267
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires