Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway

BACKGROUND: Although in recent years, the introduction of novel chemotherapy protocols has improved the outcome of T cell acute lymphoblastic leukemia (T-ALL) patients, refractory and/or relapsing disease remains a foremost concern. In this context, a major contribution was provided by the introduct...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Lonetti, Annalisa, Cappellini, Alessandra, Bertaina, Alice, Locatelli, Franco, Pession, Andrea, Buontempo, Francesca, Evangelisti, Camilla, Evangelisti, Cecilia, Orsini, Ester, Zambonin, Laura, Neri, Luca Maria, Martelli, Alberto Maria, Chiarini, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075755/
https://ncbi.nlm.nih.gov/pubmed/27776559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0344-4
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