Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignant hematological disorder arising in the thymus from T-cell progenitors. T-ALL mainly affects children and young adults, and remains fatal in 20% of adolescents and 50% of adults, despite progress in polychemotherapy protocols. Ther...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bressanin, Daniela, Evangelisti, Camilla, Ricci, Francesca, Tabellini, Giovanna, Chiarini, Francesca, Tazzari, Pier Luigi, Melchionda, Fraia, Buontempo, Francesca, Pagliaro, Pasqualepaolo, Pession, Andrea, McCubrey, James A., Martelli, Alberto M.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2012
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478458/
https://ncbi.nlm.nih.gov/pubmed/22885370
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