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Selective Immunoproteasome Inhibitors with Non-Peptide Scaffolds Identified from Structure-Based Virtual Screening
As a major component of the crucial nonlysosomal protein degradation pathway in the cells, the proteasome has been implicated in many diseases such as Alzheimer’s disease, Huntington’s disease, inflammatory bowel diseases, autoimmune diseases, multiple myeloma (MM) and other cancers. There are two m...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110913/ https://ncbi.nlm.nih.gov/pubmed/24913713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.05.025 |
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