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Value of preapproval safety data in predicting postapproval hepatic safety and assessing the legitimacy of class warning

Objective: The objective of this study was to systematically evaluate whether preapproval safety data for nonhepatotoxic drugs and hepatotoxic drugs can be compared to improve preapproval prediction of postapproval hepatic safety and to assess the legitimacy of applying class warnings. Methods: Drug...

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Главные авторы: Lin, Yeong-Liang, Wu, Ya-Chi, Gau, Churn-Shiouh, Lin, Min-Shung
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publications 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110826/
https://ncbi.nlm.nih.gov/pubmed/25083222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2042098611425183
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