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Characteristics of Preapproval and Postapproval Studies for Drugs Granted Accelerated Approval by the US Food and Drug Administration

IMPORTANCE: Drugs treating serious or life-threatening conditions can receive US Food and Drug Administration (FDA) accelerated approval based on showing an effect in surrogate measures that are only reasonably likely to predict clinical benefit. Confirmatory trials are then required to determine wh...

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Bibliografiske detaljer
Udgivet i:JAMA
Main Authors: Naci, Huseyin, Smalley, Katelyn R., Kesselheim, Aaron S.
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817559/
https://ncbi.nlm.nih.gov/pubmed/28810023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2017.9415
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