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Value of preapproval safety data in predicting postapproval hepatic safety and assessing the legitimacy of class warning

Objective: The objective of this study was to systematically evaluate whether preapproval safety data for nonhepatotoxic drugs and hepatotoxic drugs can be compared to improve preapproval prediction of postapproval hepatic safety and to assess the legitimacy of applying class warnings. Methods: Drug...

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Autors principals: Lin, Yeong-Liang, Wu, Ya-Chi, Gau, Churn-Shiouh, Lin, Min-Shung
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110826/
https://ncbi.nlm.nih.gov/pubmed/25083222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2042098611425183
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