Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis

The c-myc proto-oncogene product, Myc, is a transcription factor that binds thousands of genomic loci(1). Recent work suggested that rather than up- and down-regulating selected groups of genes(1-3), Myc targets all active promoters and enhancers in the genome (a phenomenon termed “invasion”) and ac...

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Bibliografiset tiedot
Päätekijät: Sabò, Arianna, Kress, Theresia R., Pelizzola, Mattia, de Pretis, Stefano, Gorski, Marcin M., Tesi, Alessandra, Morelli, Marco J., Bora, Pranami, Doni, Mirko, Verrecchia, Alessandro, Tonelli, Claudia, Fagà, Giovanni, Bianchi, Valerio, Ronchi, Alberto, Low, Diana, Müller, Heiko, Guccione, Ernesto, Campaner, Stefano, Amati, Bruno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110711/
https://ncbi.nlm.nih.gov/pubmed/25043028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13537
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