Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis

The c-myc proto-oncogene product, Myc, is a transcription factor that binds thousands of genomic loci(1). Recent work suggested that rather than up- and down-regulating selected groups of genes(1-3), Myc targets all active promoters and enhancers in the genome (a phenomenon termed “invasion”) and ac...

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Detalhes bibliográficos
Main Authors: Sabò, Arianna, Kress, Theresia R., Pelizzola, Mattia, de Pretis, Stefano, Gorski, Marcin M., Tesi, Alessandra, Morelli, Marco J., Bora, Pranami, Doni, Mirko, Verrecchia, Alessandro, Tonelli, Claudia, Fagà, Giovanni, Bianchi, Valerio, Ronchi, Alberto, Low, Diana, Müller, Heiko, Guccione, Ernesto, Campaner, Stefano, Amati, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110711/
https://ncbi.nlm.nih.gov/pubmed/25043028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13537
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