CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

We previously showed that immature CD166(+) osteoblasts (OB) promote hematopoietic stem cell (HSC) function. Here, we demonstrate that CD166 is a functional HSC marker that identifies both murine and human long-term repopulating cells. Both murine LSKCD48(−)CD166(+)CD150(+) and LSKCD48(−)CD166(+)CD1...

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Détails bibliographiques
Auteurs principaux: Chitteti, Brahmananda Reddy, Kobayashi, Michihiro, Cheng, Yinghua, Zhang, Huajia, Poteat, Bradley A., Broxmeyer, Hal E., Pelus, Louis M., Hanenberg, Helmut, Zollman, Amy, Kamocka, Malgorzata M., Carlesso, Nadia, Cardoso, Angelo A., Kacena, Melissa A., Srour, Edward F.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2014
Sujets:
Hematopoiesis and Stem Cells
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110658/
https://ncbi.nlm.nih.gov/pubmed/24740813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-565721
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