CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche

We previously showed that immature CD166(+) osteoblasts (OB) promote hematopoietic stem cell (HSC) function. Here, we demonstrate that CD166 is a functional HSC marker that identifies both murine and human long-term repopulating cells. Both murine LSKCD48(−)CD166(+)CD150(+) and LSKCD48(−)CD166(+)CD1...

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主要な著者: Chitteti, Brahmananda Reddy, Kobayashi, Michihiro, Cheng, Yinghua, Zhang, Huajia, Poteat, Bradley A., Broxmeyer, Hal E., Pelus, Louis M., Hanenberg, Helmut, Zollman, Amy, Kamocka, Malgorzata M., Carlesso, Nadia, Cardoso, Angelo A., Kacena, Melissa A., Srour, Edward F.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2014
主題:
Hematopoiesis and Stem Cells
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110658/
https://ncbi.nlm.nih.gov/pubmed/24740813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-565721
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