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Osteoblast lineage cells expressing high levels of Runx2 enhance hematopoietic progenitor cell proliferation and function

Although osteoblasts (OB) play a key role in the hematopoietic stem cell (HSC) niche, little is known as to which specific OB lineage cells are critical for the enhancement of stem and progenitor cell function. Unlike hematopoietic cells, OB cell surface phenotypic definitions are not well developed...

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Autors principals: Chitteti, Brahmananda R., Cheng, Ying-Hua, Streicher, Drew A., Rodriguez-Rodriguez, Sonia, Carlesso, Nadia, Srour, Edward F., Kacena, Melissa A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050482/
https://ncbi.nlm.nih.gov/pubmed/20506198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22694
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