Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function

Hematopoietic stem (HSC) and progenitor (HPC) cell fate is governed by intrinsic and extrinsic parameters. We examined the impact of hematopoietic niche elements on HSC and HPC function by analyzing the combined effect of osteoblasts (OBs) and stromal cells (SCs) on Lineage(−)Sca-1(+)CD117(+) (LSK)...

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Bibliografski detalji
Glavni autori: Chitteti, Brahmananda R., Cheng, Ying-Hua, Poteat, Bradley, Rodriguez-Rodriguez, Sonia, Goebel, W. Scott, Carlesso, Nadia, Kacena, Melissa A., Srour, Edward F.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Hematopoiesis and Stem Cells
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858485/
https://ncbi.nlm.nih.gov/pubmed/20154218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-246173
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