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Primate evolution of the recombination regulator PRDM9
The PRDM9 gene encodes a protein with a highly variable tandem-repeat zinc finger (ZF) DNA-binding domain that plays a key role in determining sequence-specific hotspots of meiotic recombination genome-wide. Here we survey the diversity of the PRDM9 ZF domain by sequencing this region in 64 primates...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110516/ https://ncbi.nlm.nih.gov/pubmed/25001002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5370 |
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