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Myopathy-causing Mutations in an HSP40 Chaperone Disrupt Processing of Specific Client Conformers
The molecular chaperone network protects against the toxic misfolding and aggregation of proteins. Disruption of this network leads to a variety of protein conformational disorders. One such example recently discovered is limb-girdle muscular dystrophy type 1D (LGMD1D), which is caused by mutation o...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4110315/ https://ncbi.nlm.nih.gov/pubmed/24920671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.572461 |
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