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Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones
TDP-43 aggregation in the cytoplasm or nucleus is a key feature of the pathology of amyotrophic lateral sclerosis and frontotemporal dementia and is observed in numerous other neurodegenerative diseases, including Alzheimer's disease. Despite this fact, the inciting events leading to TDP-43 agg...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857952/ https://ncbi.nlm.nih.gov/pubmed/23962724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt408 |
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