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Client processing is altered by novel myopathy-causing mutations in the HSP40 J domain
The misfolding and aggregation of proteins is often implicated in the development and progression of degenerative diseases. Heat shock proteins (HSPs), such as the ubiquitously expressed Type II Hsp40 molecular chaperone, DNAJB6, assist in protein folding and disaggregation. Historically, mutations...
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| Udgivet i: | PLoS One |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7272046/ https://ncbi.nlm.nih.gov/pubmed/32497100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234207 |
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