Characterising the Inhibitory Actions of Ceramide upon Insulin Signaling in Different Skeletal Muscle Cell Models: A Mechanistic Insight

Ceramides are known to promote insulin resistance in a number of metabolically important tissues including skeletal muscle, the predominant site of insulin-stimulated glucose disposal. Depending on cell type, these lipid intermediates have been shown to inhibit protein kinase B (PKB/Akt), a key medi...

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Detalhes bibliográficos
Main Authors: Mahfouz, Rana, Khoury, Rhéa, Blachnio-Zabielska, Agnieszka, Turban, Sophie, Loiseau, Nicolas, Lipina, Christopher, Stretton, Clare, Bourron, Olivier, Ferré, Pascal, Foufelle, Fabienne, Hundal, Harinder S., Hajduch, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109934/
https://ncbi.nlm.nih.gov/pubmed/25058613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0101865
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