Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE

In vivo, ectopic accumulation of fatty acids in muscles leads to alterations in insulin signaling at both the IRS1 and Akt steps. However, in vitro treatments with saturated fatty acids or their derivative ceramide demonstrate an effect only at the Akt step. In this study, we adapted our experimenta...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Hage Hassan, Rima, Pacheco de Sousa, Ana Catarina, Mahfouz, Rana, Hainault, Isabelle, Blachnio-Zabielska, Agnieszka, Bourron, Olivier, Koskas, Fabien, Górski, Jan, Ferré, Pascal, Foufelle, Fabienne, Hajduch, Eric
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2016
विषय:
Metabolism
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742763/
https://ncbi.nlm.nih.gov/pubmed/26698173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.686949
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