LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice

A key step in plasma HDL maturation from discoidal to spherical particles is the esterification of cholesterol to cholesteryl ester, which is catalyzed by LCAT. HDL-like lipoproteins in cerebrospinal fluid (CSF) are also spherical, whereas nascent lipoprotein particles secreted from astrocytes are d...

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Detalhes bibliográficos
Main Authors: Stukas, Sophie, Freeman, Lita, Lee, Michael, Wilkinson, Anna, Ossoli, Alice, Vaisman, Boris, Demosky, Stephen, Chan, Jeniffer, Hirsch-Reinshagen, Veronica, Remaley, Alan T., Wellington, Cheryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109766/
https://ncbi.nlm.nih.gov/pubmed/24950691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M049940
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