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Minimally oxidized LDL inhibits macrophage selective cholesteryl ester uptake and native LDL-induced foam cell formation

Scavenger receptor-mediated uptake of oxidized LDL (oxLDL) is thought to be the major mechanism of foam cell generation in atherosclerotic lesions. Recent data has indicated that native LDL is also capable of contributing to foam cell formation via low-affinity receptor-independent LDL particle pino...

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Autors principals: Meyer, Jason M., Ji, Ailing, Cai, Lei, van der Westhuyzen, Deneys R.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109759/
https://ncbi.nlm.nih.gov/pubmed/24891335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M044644
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