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High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation

Macrophage foam cells are a defining pathologic feature of atherosclerotic lesions. Recent studies have demonstrated that at high concentrations associated with hypercholesterolemia, native LDL induces macrophage lipid accumulation. LDL particles are taken up by macrophages as part of bulk fluid pin...

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Detalhes bibliográficos
Main Authors: Meyer, Jason M., Ji, Ailing, Cai, Lei, van der Westhuyzen, Deneys R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435541/
https://ncbi.nlm.nih.gov/pubmed/22833685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026534
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