Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages

Scavenger receptor BI (SR-BI), an HDL receptor, plays a key role in reverse cholesterol transport. In mice, disruption of SR-BI results in hypersensitivity to lipopolysaccharide (LPS) and bacteria-induced septic shock due to adrenal insufficiency and abnormal hepatic pathogen clearance. In this stud...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cai, Lei, Wang, Zhen, Meyer, Jason M., Ji, Ailing, van der Westhuyzen, Deneys R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540840/
https://ncbi.nlm.nih.gov/pubmed/22589557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M023234
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