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Macrophage SR-BI regulates LPS-induced pro-inflammatory signaling in mice and isolated macrophages
Scavenger receptor BI (SR-BI), an HDL receptor, plays a key role in reverse cholesterol transport. In mice, disruption of SR-BI results in hypersensitivity to lipopolysaccharide (LPS) and bacteria-induced septic shock due to adrenal insufficiency and abnormal hepatic pathogen clearance. In this stud...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3540840/ https://ncbi.nlm.nih.gov/pubmed/22589557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M023234 |
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