Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI

To study the mechanisms of hepatic HDL formation, we investigated the roles of ABCA1, ABCG1, and SR-BI in nascent HDL formation in primary hepatocytes isolated from mice deficient in ABCA1, ABCG1, or SR-BI and from wild-type (WT) mice. Under basal conditions, in WT hepatocytes, cholesterol efflux to...

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Detalhes bibliográficos
Main Authors: Ji, Ailing, Wroblewski, Joanne M., Cai, Lei, de Beer, Maria C., Webb, Nancy R., van der Westhuyzen, Deneys R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276468/
https://ncbi.nlm.nih.gov/pubmed/22190590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M017079
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