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Upregulation of hepatic VLDLR via PPARα is required for the triglyceride-lowering effect of fenofibrate
The liver and the VLDL receptor (VLDLR) play major roles in TG and VLDL metabolism. However, the exact role of liver VLDLR is not well known because of the absence of or difficulty in detecting VLDLR in the liver. In this study, we demonstrate that fenofibrate, a PPARα agonist and widely used TG-low...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109757/ https://ncbi.nlm.nih.gov/pubmed/24899625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M041988 |
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