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Upregulation of hepatic VLDLR via PPARα is required for the triglyceride-lowering effect of fenofibrate

The liver and the VLDL receptor (VLDLR) play major roles in TG and VLDL metabolism. However, the exact role of liver VLDLR is not well known because of the absence of or difficulty in detecting VLDLR in the liver. In this study, we demonstrate that fenofibrate, a PPARα agonist and widely used TG-low...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gao, Yang, Shen, Wei, Lu, Boyu, Zhang, Qingjiong, Hu, Yang, Chen, Ying
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Biochemistry and Molecular Biology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109757/
https://ncbi.nlm.nih.gov/pubmed/24899625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M041988
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