Fenofibrate Ameliorates Hepatic Ischemia/Reperfusion Injury in Mice: Involvements of Apoptosis, Autophagy, and PPAR-α Activation

Hepatic ischemia and reperfusion injury is characterized by hepatocyte apoptosis, impaired autophagy, and oxidative stress. Fenofibrate, a commonly used antilipidemic drug, has been verified to exert hepatic protective effects in other cells and animal models. The purpose of this study was to identi...

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Veröffentlicht in:PPAR Res
Hauptverfasser: Zhang, Jie, Cheng, Ping, Dai, Weiqi, Ji, Jie, Wu, Liwei, Feng, Jiao, Wu, Jianye, Yu, Qiang, Li, Jingjing, Guo, Chuanyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870311/
https://ncbi.nlm.nih.gov/pubmed/33603777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6658944
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