CCAAT/Enhancer-binding Protein β Deletion Reduces Adiposity, Hepatic Steatosis, and Diabetes in Lepr(db/db) Mice()

CCAAT/enhancer-binding protein β (C/EBPβ) plays a key role in initiation of adipogenesis in adipose tissue and gluconeogenesis in liver; however, the role of C/EBPβ in hepatic lipogenesis remains undefined. Here we show that C/EBPβ inactivation in Lepr(db/db) mice attenuates obesity, fatty liver, an...

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Detalhes bibliográficos
Main Authors: Schroeder-Gloeckler, Jill M., Rahman, Shaikh Mizanoor, Janssen, Rachel C., Qiao, Liping, Shao, Jianhua, Roper, Michael, Fischer, Stephanie J., Lowe, Erin, Orlicky, David J., McManaman, James L., Palmer, Carol, Gitomer, William L., Huang, Wan, O’Doherty, Robert M., Becker, Thomas C., Klemm, Dwight J., Jensen, Dalan R., Pulawa, Leslie K., Eckel, Robert H., Friedman, Jacob E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109269/
https://ncbi.nlm.nih.gov/pubmed/17387171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701329200
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