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CCAAT/Enhancer-binding Protein β Deletion Reduces Adiposity, Hepatic Steatosis, and Diabetes in Lepr(db/db) Mice()

CCAAT/enhancer-binding protein β (C/EBPβ) plays a key role in initiation of adipogenesis in adipose tissue and gluconeogenesis in liver; however, the role of C/EBPβ in hepatic lipogenesis remains undefined. Here we show that C/EBPβ inactivation in Lepr(db/db) mice attenuates obesity, fatty liver, an...

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Détails bibliographiques
Auteurs principaux: Schroeder-Gloeckler, Jill M., Rahman, Shaikh Mizanoor, Janssen, Rachel C., Qiao, Liping, Shao, Jianhua, Roper, Michael, Fischer, Stephanie J., Lowe, Erin, Orlicky, David J., McManaman, James L., Palmer, Carol, Gitomer, William L., Huang, Wan, O’Doherty, Robert M., Becker, Thomas C., Klemm, Dwight J., Jensen, Dalan R., Pulawa, Leslie K., Eckel, Robert H., Friedman, Jacob E.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109269/
https://ncbi.nlm.nih.gov/pubmed/17387171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M701329200
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