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Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8()

The glycoprotein milk fat globule-EGF factor 8 (MFG-E8) is expressed in several tissues and mediates diverse homeostatic functions. However, whether MFG-E8 plays a role in bone homeostasis has not been established. Here we show for the first time that osteoclasts express and are regulated by MFG-E8....

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Detalhes bibliográficos
Main Authors: Abe, Toshiharu, Shin, Jieun, Hosur, Kavita, Udey, Mark C., Chavakis, Triantafyllos, Hajishengallis, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108495/
https://ncbi.nlm.nih.gov/pubmed/24958900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400970
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