Inflammatory bone loss associated with MFG-E8 deficiency is rescued by teriparatide

A prolonged increase in proinflammatory cytokines is associated with osteoporotic and autoimmune bone loss and, conversely, anti-inflammatory pathways are associated with protection against bone loss. Milk fat globule-epidermal growth factor (MFG-E)-8 is a glycoprotein that is proresolving, regulate...

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Veröffentlicht in:FASEB J
Hauptverfasser: Michalski, Megan N., Seydel, Anna L., Siismets, Erica M., Zweifler, Laura E., Koh, Amy J., Sinder, Benjamin P., Aguirre, J. Ignacio, Atabai, Kamran, Roca, Hernan, McCauley, Laurie K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2018
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998979/
https://ncbi.nlm.nih.gov/pubmed/29475373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201701238R
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