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Bone Mass is Compromised by the Chemotherapeutic Trabectedin in Association with Effects on Osteoblasts and Macrophage Efferocytosis

Macrophages have established roles supporting bone formation. Despite their professional phagocytic nature, the role of macrophage phagocytosis in bone homeostasis is not well understood. Interestingly, apoptosis is a pivotal feature of cellular regulation and the primary fate of osteoblasts is apop...

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Bibliographische Detailangaben
Veröffentlicht in:J Bone Miner Res
Hauptverfasser: Sinder, Benjamin P., Zweifler, Laura, Koh, Amy J., Michalski, Megan N., Hofbauer, Lorenz C., Aguirre, Jose Ignacio, Roca, Hernan, McCauley, Laurie K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640484/
https://ncbi.nlm.nih.gov/pubmed/28600866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3196
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