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Bone Mass is Compromised by the Chemotherapeutic Trabectedin in Association with Effects on Osteoblasts and Macrophage Efferocytosis

Macrophages have established roles supporting bone formation. Despite their professional phagocytic nature, the role of macrophage phagocytosis in bone homeostasis is not well understood. Interestingly, apoptosis is a pivotal feature of cellular regulation and the primary fate of osteoblasts is apop...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Sinder, Benjamin P., Zweifler, Laura, Koh, Amy J., Michalski, Megan N., Hofbauer, Lorenz C., Aguirre, Jose Ignacio, Roca, Hernan, McCauley, Laurie K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5640484/
https://ncbi.nlm.nih.gov/pubmed/28600866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.3196
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