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MFG-E8 inhibits periodontitis in non-human primates and its gingival crevicular fluid levels can differentiate periodontal health from disease in humans

AIM: We have previously shown that the secreted glycoprotein MFG-E8 has anti-inflammatory and anti-osteoclastogenic properties. Our objective was to investigate the potential of MFG-E8 as a diagnostic or therapeutic agent in periodontitis. MATERIALS AND METHODS: Periodontitis was induced in non-huma...

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Vydáno v:J Clin Periodontol
Hlavní autoři: Kajikawa, Tetsuhiro, Meshikhes, Fatimah, Maekawa, Tomoki, Hajishengallis, Evlambia, Hosur, Kavita B., Abe, Toshiharu, Moss, Kevin, Chavakis, Triantafyllos, Hajishengallis, George
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433891/
https://ncbi.nlm.nih.gov/pubmed/28207941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcpe.12707
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