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T-Cells Null for the MED23 Subunit of Mediator Express Decreased Levels of KLF2 and Inefficiently Populate the Peripheral Lymphoid Organs

MED23, a subunit of the Mediator coactivator complex, is important for the expression of a subset of MAPK/ERK pathway-responsive genes, the constituents of which vary between cell types for reasons that are not completely clear. MAPK/ERK pathway-dependent processes are essential for T-cell developme...

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Detalhes bibliográficos
Main Authors: Kasper, Lawryn H., Fukuyama, Tomofusa, Brindle, Paul K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108324/
https://ncbi.nlm.nih.gov/pubmed/25054639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102076
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