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T cells require Foxo1 to populate the peripheral lymphoid organs

Forkhead (Fox) transcription factors play critical roles in leukocyte homeostasis. To study further the immunological functions of Foxo1, we generated mice that selectively lack Foxo1 in T cells (Foxo1 cKO). Although thymocyte development appeared relatively normal, Foxo1 cKO mice harbored significa...

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Detalhes bibliográficos
Main Authors: Bupp, Melanie Gubbels, Edwards, Bonnie, Guo, Caiying, Wei, Datsen, Chen, Gang, Wong, Brian, Masteller, Emma, Peng, Stanford L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010613/
https://ncbi.nlm.nih.gov/pubmed/19658095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939427
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