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Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease1 (APE1/Ref-1) via recruitment of histone deacetylase1corepressor complex
OBJECTIVES: Apurinic/apyrimidinic-endonuclease 1 (APE1) heterozygous mice have chronically elevated blood pressure. Renin of the renin–angiotensin (ANG) system for blood pressure maintenance regulates production of ANG II, a vasoactive hormone. Renin expression and secretion from kidney juxtaglomeru...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4108083/ https://ncbi.nlm.nih.gov/pubmed/22441348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e3283525124 |
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