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Regulation of mouse-renin gene by apurinic/apyrimidinic-endonuclease1 (APE1/Ref-1) via recruitment of histone deacetylase1corepressor complex

OBJECTIVES: Apurinic/apyrimidinic-endonuclease 1 (APE1) heterozygous mice have chronically elevated blood pressure. Renin of the renin–angiotensin (ANG) system for blood pressure maintenance regulates production of ANG II, a vasoactive hormone. Renin expression and secretion from kidney juxtaglomeru...

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Hlavní autoři: Sengupta, Shiladitya, Chattopadhyay, Ranajoy, Mantha, Anil K., Mitra, Sankar, Bhakat, Kishor K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108083/
https://ncbi.nlm.nih.gov/pubmed/22441348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e3283525124
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