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Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein

The mammalian AP-endonuclease (APE1/Ref-1) plays a central role in the repair of oxidized and alkylated bases in mammalian genomes via the base excision repair (BER) pathway. However, APE1, unlike its E. coli prototype Xth, has two unique and apparently distinct transcriptional regulatory activities...

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Hlavní autoři: Bhakat, Kishor K., Mantha, Anil K., Mitra, Sankar
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933571/
https://ncbi.nlm.nih.gov/pubmed/18715144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2198
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