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Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein

The mammalian AP-endonuclease (APE1/Ref-1) plays a central role in the repair of oxidized and alkylated bases in mammalian genomes via the base excision repair (BER) pathway. However, APE1, unlike its E. coli prototype Xth, has two unique and apparently distinct transcriptional regulatory activities...

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Bibliografiske detaljer
Main Authors: Bhakat, Kishor K., Mantha, Anil K., Mitra, Sankar
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933571/
https://ncbi.nlm.nih.gov/pubmed/18715144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2198
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