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Regulatory interactions between RNA and Polycomb Repressive Complex 2
Polycomb repressive complex 2 (PRC2) is a histone methyltransferase that is localized to thousands of mammalian genes. Though important to human disease and as a drug target, how PRC2 is recruited remains unclear. One model invokes cis-regulatory RNA. Herein, we biochemically and functionally probe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4107928/ https://ncbi.nlm.nih.gov/pubmed/24882207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.05.009 |
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